Course Registration

Registration on Courses will be offered during the Registration process and start in June 2,  2016.

After October 20, 2016 will not be guaranteed course material for new participants.

Course fee in reais:

                                        Member                                         Non-member 

                      until 10 nov            after 10 nov                 until 10 nov         after 10 nov 

Professionals           460                     530                          530                     610

Students                 345                     400                         400                     460


To Register click here.


Courses fee includes:

Access to the selected 6h course. From 9am to 12 am and then from 2pm to 5 pm 

Lunch is included and will be served at the restaurant of the Windsor Barra Hotel.

Note that all courses runs exactly on the same schedule, so it is not possible to register for more than one course.



07:00H – 08:50H -   On site Registration and Welcome breakfast
08:50H - 10:20H -    MS Courses
10:20H - 10:35H -    Coffee Break
10:35H – 12:00H -    MS Courses
12:00H - 14:00H -    Lunch
14:00H – 15:45H -    MS Courses
15:45H - 16:00H -    Coffee Break
16:00H - 17:00H -    MS Courses


QUELUZ I (1st Floor)

COURSE 1: Mass Spectrum Interpretation- EI-MS e ESI-MS/MS (CONFIRMED)

Instructors:  Marcos N. Eberlin, Ph.D. (IQ/UNICAMP), Rodinei Augusti, Ph.D. (UFMG) and Gianluca Giorgi, Ph. D. (Università di Siena, Italia)

Language: Portuguese

-      Main Rules applied on mass spectra interpretation and fragmentation of molecular ion and protonated and deprotonated molecules

-      Protonated molecules, sodium and potassium aducts

-      Isotopologues and isotope standards

-      Mass defect, exact mass and molecular formula

-      Main fragmentation types: alpha cleavage, inductive cleavage, hydrogen rearragements

-      Pair electron rule, nitrogen rule

-      Logic and Ilogic fragmentation

-      Structure x reactivity relationship

-      Diverse examples


Venezia I (2nd Floor)

COURSE 4: Fragmentation reactions using electrospray ionization mass spectrometry: an important tool for the structural elucidation and characterization of synthetic and natural products  (CONFIRMED)

Instructors: Norberto Peporine Lopes, Ph.D. (Núcleo de Pesquisa em Produtos Naturais e Sintéticos, Faculdade de Ciências Farmacêuticas de Ribeirão Preto – USP)

Language: Portuguese

The aim of this course is the analysis of natural and synthetic products and complex organic molecules by tandem and sequential mass spectrometry - especially using electrospray ionisation and collision induced dissociation. The course has generally interested in all areas of modern mass spectrometry, especially those applied to ion fragmentation studies and gas-phase chemistry.

Soft Ionization Methods and Analysers in Instrumentation

In Source Ionization Reactions

Mechanism of Fragmentation Reactions in CID activation.


Venezia II (2nd Floor)

COURSE 5: Gas chromatography coupled to mass spectrometry (GC/MS): principles, methods and applications  (CONFIRMED)

Instructors: Oscar Vega Bustillos, Ph.D. (IPEN/CNEN-SP).

Language: Portuguese

Historical development and fundamental concepts in Gas Chromatography coupled to Mass Spectrometry GC/MS. Principles and methods of the Gas Chromatography technique such as sample injectors: On-column, Split/split-less, Purge-and-Trap, Thermal Desorption and Gas Switching Valve. Chromatography Columns: Stationary phase, carrier gas flow rate, column length, column thickness and column temperature program. Chromatography detectors: TCD, FID, ECD and MS. Principles and methods of the Mass Spectrometry such as: Ionization sources EI and CI. Mass analyzers: Magnetic sectors, Quadrupole mass filter, Ion-Trap, Tandem systems. Ion detection: Faraday cup and Electron multiplier. Pressure and interphase system of the GC/MS: High pressure, atmospheric pressure and Vacuum. Hybrid systems Gas Chromatography coupled Mass Spectrometry GC/MS-MS. Interpretation of chromatogram and mass spectra obtained in different ionization modes. Sample preparation for analysis by GC/MS such as: Soxhlet, SPE, Quechers and micro-extraction. Validation protocols of analytical methods. Applications of the GC/MS technique in the analyses of pesticides in food, drugs abuse, environmental samples, and restoration of art paintings.


Venezia III (2nd Floor)

COURSE 6: Mass Spectrometry for Natural Products Analysis  (CONFIRMED) 

Instructors: Jimmy Yuk, Ph.D. and Michael Murgu, Ph.D. - Waters Corporation

Language: Portuguese

The course will cover strategies and techniques for studying Natural products using Mass Spectrometry, including metabolomics, phytotherapeutics quality control, identification of Natural products, sample preparation, quantification and MS imaging, using different MS techniques like high resolution MS and tandem quadrupole MS.


Out of Hotel

COURSE 10: Toxicology and doping analyses by MS (CONFIRMED)

Instructors: Prof. Dr. Francisco Radler, Prof. Dra. Monica Padilha, Prof. Dr. Vinicius Sardela e Msc. Fábio Azamor

Language: Portuguese

The aim of this course is to present the technics to prepare samples and analyses for screening and confirmation of abuse drugs and its metabolites and others compounds of toxicological interest, doping and forensic, using GC/MS and LC/MS with Triple-quadrupole and Orbitrap analyzer.

This course is for users of MS analyzers for biological samplers with expertise in any kind of technology or to beginners that wish to learn more about those technology.

Mini Curso Toxicologia.pdf


VENEZIA IV (2nd Floor)

COURSE 15: Advanced mass spectrometry-based proteomics for Post-Translational Modifications (PTMs) analysis  (CONFIRMED)

Instructors: Giuseppe Palmisano, Ph.D. - GlycoProteomics Laboratory, Department of

Parasitology, University of Sao Paulo, Brazil

Language: Portuguese

This course aims at: 1) providing a complementary perspective on the use of mass spectrometry to identify and quantify protein PTMs. Due to the importance of PTMs in several scientific fields, this course will 2) present the state-of-the-art instrumentation and sample preparation for PTMs analysis using mass spectrometry. 3) Offer new possibilities to implement PTMs analysis in the students’ laboratories. 4) Expand the repertoire of tools available in the proteomic field. 5) Highlight the capabilities of mass spectrometry to identify and quantify PTMs in large-scale experiments.

The theoretical part of the course will be divided in three main parts: 1) biological significance of PTMs, 2) enrichment methods and 3) mass spectrometry-based proteomics analysis of PTMs. There will be a group discussion that will aim at giving suggestions to improve the field.


VENEZIA V (2nd Floor)

COURSE 16: Hair Testing for Drugs of abuse: from sample preparation to the final results using GC-MS and LC-MS.  (CONFIRMED)

Instructors: Agilent

Language: Portuguese

Drugs of abuse represents a problem in today’s society and affects all classes with devastating effects. Concerned with this situation, from March 2016 a new regulation (Portaria MTPS Nº 116 DE 13/11/2015) started in Brazil which requires that professional drivers to make tests for different classes of drugs of abuse (eg. THC, Cocaine, Opiates, Amphetamines). The analysis will test the potential use of these compounds in a minimum time window of 90 days.

 The limits of detection and quantitation are very low and the application of specific sample prep and high end analytical instruments are required to ensure the quality of results, avoiding false positives and negatives

The goal of this course is to present to the participant details about the metabolism and physiology of the drugs of abuse in the human body and why chooses hair as matrix. What are the better alternatives for sample prep and the consumables necessary to ensure an efficient drug extraction and finally, which are the best techniques presenting the fundamentals of Mass Spectrometry (GC and LCMS), considering their differences, costs, complexity and adequacy according with the drug to be analyzed.


DUCALE I (2nd Floor)

COURSE 18: Use of Bruker tools for characterization and identification of natural products, metabolites, degradation products and small molecules data acquired with high resolution and mass accuracy ESI-TOF MS. (CONFIRMED)

Instructors: Luiz Fernando Arruda Santos, Ph.D. - Bruker

Language: Depending on the audience, the course can be provided in English, Portuguese or Spanish.

The course will provide a basic introduction to electrospray quadrupole time of flight mass spectrometry theory. But the main goal of this course, that is actually a data analysis training, is to show the Bruker tools that are part of DataAnalysis software to process and analyze data of natural products, metabolites, degradation products and small molecules in general, acquired with Bruker ESI-TOF instruments. Topics included, but not restricted to, are: molecular formula proposition based on exact mass, isotope pattern and fragments (SmartFormula and SmartFormula 3D); submission of molecular formulas to on-line data bases (CompoundCrawler); MS and MS/MS spectra annotation using Annotate and Building Blocks tools; MS/MS spectra interpretation with support of FragmentExplorer drawing tool; direct submission of MS/MS spectra to on-line in-silico databases (Met-Frag); data calibration; extracted ion chromatograms (EIC) and other chromatogram traces; and more.


DUCALE II (2nd Floor)

COURSE 22: Mass spectrometry in forensic chemistry, forensic toxicology and clinical toxicology  (CONFIRMED)

Instructors: José Luiz da Costa, Ph.D. (FCF/UNICAMP), Célio F. F. Angolini, Ph.D. (IQ/UNICAMP), Rafael Lanaro (CCI/UNICAMP) e Elvis Medeiros de Aquino (Superintedência da Polícia Técnico-Cinetífica-SP), Pablo Alves Marinho, MS.C. (Perito Criminal Chefe da Divisão de Laboratório, Instituto de Criminalística - Policia Civil  - Belo Horizonte/MG); Daniel Saidemberg, PhD (Shimadzu do Brazil); Lucas Marinho Nobrega de Assis, PhD (Shimadzu do Brazil)

Language: Portuguese

Mass spectrometry is a powerful analytical tool, widely used in forensic and clinical laboratories. In this course, key points of analytical toxicology and forensic chemistry will be discussed including: different chromatographic and MS techniques used in forensic and clinical labs, sample selection and sample preparation in analytical toxicology, method development, validation and interpretation of analytical toxicology findings. Special focus will be made on identification of classical and New Psychoactive Substances (NPS), in seized materials and biological samples (blood, urine, hair). The presenters have extensive experience in toxicology and forensic chemistry, and they will use real case reports to illustrate the Instructorss. The main topics of course will be:

- Ambient mass spectrometry in forensic chemistry

- Identification of New Psychoactive Substances (NPS): how to deal with this nightmare?

- Mass spectrometry in post mortem forensic toxicology

- Diagnosis of acute intoxication by mass spectrometry: the role of MS in urgency/emergency hospital

- Sample preparation and method validation in forensic and clinical toxicology.

- New trends in elemental analysis: the use of ICP and ICP-MS for toxicology

- Analysis of Drugs and Poisons in Biological Fluids and Human Hair

- Forensic and Toxicological Analysis Using Mass Spectrometry: new solutions


DUCALE III (2nd Floor)

COURSE 24: Methods Validation with approach on mass spectrometry  (CONFIRMED)

Instructors: Heliara Nascimento, Ph.D. (IQ-UNICAMP)

Language: Portuguese

Integration of Validation to Quality Systems;

Validation in GLP and ISO 17025;

Requirements for the choice of an analytical method;

Analytical method Traceability;

Validation Laws and Rules;

Validation Criteria used by creditation and international organizations;

Validation Basic Concepts;

Validation Parameters: precision, accuracy, linearity, selectivity, specificity, limit of quantification (LOQ), limit of detection (LOD), robustness;

Mass Spectrometry technique: method validation cautions on GC-MS and LC-MS;

Real data analysis on a validation - practical examples;

Conclusion – technique summary.



COURSE 26: Proteomics  (CONFIRMED)

Instructors: Fábio Gozzo, PH.D. (IQ/UNICAMP), Paulo Carvalho, Ph.D. (Fiocruz) and Diogo Borges

Language: Portuguese

. Protein and mass spectrometry fundamentals

. Fragmentation of peptides

. Spectrum Interpretation

. Shotgun proteomics

. Peptide identification

. Modifications

. Quantitative analysis

. Data Quality control



Course 27: Mass Spectrometry for Non-Targeted and Quantitative Lipidomics  (CONFIRMED)

Instructors: SCIEX

Language: Portuguese

The interest of lipid analysis by mass spectrometry has increased to understand the biological functions of a cell system, but the lipidomics analysis is still a challenge to detect as many individual lipids as possible due the isobaric interferences from overlapping lipid species within the same m/z range and the complicated sample preparation. This course will focus in workflows that include simplified automated methods and streamlined data processing techniques that enable facile, quantitative lipid analysis. We will discuss some workflows like: i) shotgun analysis, that is able to identify molecular species of most major and many minor lipid classes that can be identified and quantitated directly from biological lipid extracts without the need for chromatographic purification; ii) a lipid analyzer named Lipidyzer Platform, a novel technique using differential mobility spectrometry (DMS) coupled with tandem mass spectrometry and a lipid data analysis software to give an easy way to make lipid analysis and, finally iii) a method for MS/MSALL analysis, a powerful tool for lipidomics research that provides automated collection of all precursors ions within a desired mass range, fragmentation of selected precursor ions, and a record of all product ions, resulting in a three-dimensional map of all lipid precursors and fragments that can be mined.



Course 28: Targeted Peptide Quantitation by Mass Spectrometry  (CONFIRMED)

Instructors: SCIEX

Language: Portuguese

Peptides are very interesting and important molecules due to their versatility. They can work like biological messenger, build block of your skin, be part of good pizza dough, or kill you as an allergen. Because that, nowadays, peptides and their amounts deserve more attention, either by housewife or scientists. During the course we will provide you the knowledge to identify major of the components of peptide backbone structure and conventional amino acids, predict general properties and charge state from peptide sequence, understand mode of peptide fragmentation in a quadrupole, associated peptide MS/MS fragments with a peptide sequence and picking MRM transitions for peptides. Troubleshooting is another import topic covered in the content. Let’s learn how to identify challenges associated with peptide quantitation such as poor fragmentation like high background, and endogenous interferences. How the use of an MRM3 and Differential Mobility Spectrometry can selectively remove background from endogenous interferences, even with poor fragmenting peptides.